BDBM784895 6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-benzothiophene-2-carboxylic acid ::6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-benzothiophene-2-carboxylic acid::US12466803, Example 9

SMILES COc1c(F)c(F)cc(-c2c(C(=O)O)sc3cc(F)ccc23)c1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 784895   

LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataKd:  4.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/2/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetBranched-chain alpha-ketoacid dehydrogenase kinase(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetBranched-chain alpha-ketoacid dehydrogenase kinase(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 41nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 46nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSolute carrier family 22 member 8(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 670nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSolute carrier family 22 member 6(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 4.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 4.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetMultidrug and toxin extrusion protein 1(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 8.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetMultidrug and toxin extrusion protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 8.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetATP-dependent translocase ABCB1(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 8.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 8.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSolute carrier family 22 member 1(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 8.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSolute carrier family 22 member 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 784895BDBM784895(6-Fluoro-3-(2,4,5-trifluoro-3-methoxyphenyl)-1-ben...)
Affinity DataIC50: 8.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed