BDBM775761 US12435090, Compound 181::US20250388583, Compound 577

SMILES Cc1cc2c(C(N)=O)c(N)n(-c3c(C)ccc(O)c3C)c2nc1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 775761   

TargetMyelin transcription factor 1(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 775761BDBM775761(US12435090, Compound 181 | US20250388583, Compound...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Engine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 775761BDBM775761(US12435090, Compound 181 | US20250388583, Compound...)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 775761BDBM775761(US12435090, Compound 181 | US20250388583, Compound...)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent