BDBM77572 5-methyl-3-phenyl-4-isoxazolecarboxylic acid [[amino-(5-nitro-2-furanyl)methylidene]amino] ester::5-methyl-3-phenyl-isoxazole-4-carboxylic acid [[amino-(5-nitro-2-furyl)methylene]amino] ester::MLS000861277::O2-[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]-5-nitrofuran-2-carbohydroximamide::SMR000460061::[[amino-(5-nitrofuran-2-yl)methylidene]amino] 5-methyl-3-phenyl-1,2-oxazole-4-carboxylate::[[azanyl-(5-nitrofuran-2-yl)methylidene]amino] 5-methyl-3-phenyl-1,2-oxazole-4-carboxylate::cid_2726624

SMILES CCc1cc(O)c(F)cc1-c1ccc2c(-c3nc4c([nH]3)CN(C(=O)NCCO)C4)n[nH]c2c1

InChI Key InChIKey=OQKXCADKZOYPNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 77572   

TargetBDNF/NT-3 growth factors receptor(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 77572BDBM77572(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol...)
Affinity DataIC50: 3.58nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 77572BDBM77572(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol...)
Affinity DataIC50: 3.77nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Medinno Pharmaceutical Technology (Zhuhai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 77572BDBM77572(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol...)
Affinity DataIC50: 12nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent