BDBM775591 US12435089, Example 69

SMILES CCCCC1NC(c2cnn3ccc(N[C@H](C)c4cc(F)ccc4O)nc23)=NO1

InChI Key InChIKey=TXKUKKMGRGZDHL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 775591   

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775591BDBM775591(US12435089, Example 69)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775591BDBM775591(US12435089, Example 69)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775591BDBM775591(US12435089, Example 69)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775591BDBM775591(US12435089, Example 69)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775591BDBM775591(US12435089, Example 69)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775591BDBM775591(US12435089, Example 69)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent