BDBM774114 US12428433, Example 2

SMILES O=C1N[C@H]2C[C@H](C2)Oc2ncc(F)cc2[C@H]2CCCN2c2nc3c1cnn3cc2F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 774114   

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774114BDBM774114(US12428433, Example 2)
Affinity DataIC50: 0.420nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774114BDBM774114(US12428433, Example 2)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774114BDBM774114(US12428433, Example 2)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent