BDBM764694 US20250257059, Example 27

SMILES O=C1CN(c2c(O)cc(CC3CCNC3)cc2F)S(=O)(=O)N1

InChI Key InChIKey=GCQFYWPWFKKSPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 764694   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 764694BDBM764694(US20250257059, Example 27)
Affinity DataIC50: 7nMAssay Description:Inhibition of full length human recombinant PTPN2 (1 to 387 residues)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein phosphatase N2 [1-387](Homo sapiens (Human))
Nerio Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 764694BDBM764694(US20250257059, Example 27)
Affinity DataIC50: 7nMAssay Description:PTPN2 was produced in E. coli as a GST-TEV fusion and the GST was removed by TEV digestion, followed by additional purification to yield full-length ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent