BDBM757350 US12357603, Example 35

SMILES Cc1cc(N(C)C)cc2oc(C(=O)NS(=O)(=O)c3ccccc3-c3ccccc3)cc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 757350   

TargetHistone acetyltransferase KAT6A(Human)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 757350BDBM757350(US12357603, Example 35)
Affinity DataIC50: 452nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 757350BDBM757350(US12357603, Example 35)
Affinity DataIC50: 452nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 757350BDBM757350(US12357603, Example 35)
Affinity DataIC50: 654nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 757350BDBM757350(US12357603, Example 35)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed