BDBM757317 6-(Methylamino)-N-(2-phenylphenyl)sulfonyl-benzofuran-2-carboxamide::US12357603, Example 11

SMILES CNc1ccc2cc(C(=O)NS(=O)(=O)c3ccccc3-c3ccccc3)oc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 757317   

TargetHistone acetyltransferase KAT6A(Human)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 757317BDBM757317(6-(Methylamino)-N-(2-phenylphenyl)sulfonyl-benzofu...)
Affinity DataIC50: 123nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 757317BDBM757317(6-(Methylamino)-N-(2-phenylphenyl)sulfonyl-benzofu...)
Affinity DataIC50: 123nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 757317BDBM757317(6-(Methylamino)-N-(2-phenylphenyl)sulfonyl-benzofu...)
Affinity DataIC50: 205nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A(Human)
Bayer AG

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 757317BDBM757317(6-(Methylamino)-N-(2-phenylphenyl)sulfonyl-benzofu...)
Affinity DataIC50: 2.58E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed