BDBM75552 2-(4-fluoranylphenoxy)-N-[4-(3,4,5,6-tetrahydro-2H-azepin-7-ylsulfamoyl)phenyl]propanamide::2-(4-fluorophenoxy)-N-[4-(3,4,5,6-tetrahydro-2H-azepin-7-ylsulfamoyl)phenyl]propanamide::2-(4-fluorophenoxy)-N-[4-(3,4,5,6-tetrahydro-2H-azepin-7-ylsulfamoyl)phenyl]propionamide::MLS002181391::SMR001270421::cid_25163852

SMILES C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccccn23)cc1

InChI Key InChIKey=LPDLDMKXPVKYOR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75552   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75552BDBM75552(2-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 10nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75552BDBM75552(2-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 55nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75552BDBM75552(2-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 550nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent