BDBM75540 5-[2-[(E)-(5-methoxy-6-oxidanylidene-cyclohexa-2,4-dien-1-ylidene)methyl]hydrazinyl]-3-methylsulfanyl-1,2-thiazole-4-carbonitrile::5-[2-[(E)-(5-methoxy-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]hydrazinyl]-3-methylsulfanyl-1,2-thiazole-4-carbonitrile::5-[N'-[(E)-(6-keto-5-methoxy-cyclohexa-2,4-dien-1-ylidene)methyl]hydrazino]-3-(methylthio)isothiazole-4-carbonitrile::5-[[(E)-(5-methoxy-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydrazo]-3-(methylthio)-4-isothiazolecarbonitrile::MLS000521542::SMR000131950::cid_6280515

SMILES C=C(F)C(=O)N1CCc2cc(-c3c(-c4ccc(Oc5nccc(C)n5)c(F)c4)c(C(N)=O)c4ccc(C)nn34)c(C)cc21

InChI Key InChIKey=ZWWMBDZCCGWVMZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75540   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75540BDBM75540(6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 10nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75540BDBM75540(6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 10nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75540BDBM75540(6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 55nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent