BDBM75538 (Z)-2-butenedioic acid;1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine::(Z)-but-2-enedioic acid;1-(3-chloranyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine::(Z)-but-2-enedioic acid;1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine::1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine;maleic acid::1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine::MLS000547068::SMR000113867::cid_9549749

SMILES C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3ccc(C)nn23)c(C)c1

InChI Key InChIKey=YITAORWEHMMACD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75538   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75538BDBM75538(6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 10nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75538BDBM75538(6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 55nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75538BDBM75538(6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 55nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent