BDBM75534 MLS001060579::N-[(3-chloranyl-4-fluoranyl-phenyl)carbamothioyl]cyclopropanecarboxamide::N-[(3-chloro-4-fluoro-phenyl)thiocarbamoyl]cyclopropanecarboxamide::N-[(3-chloro-4-fluoroanilino)-sulfanylidenemethyl]cyclopropanecarboxamide::N-[(3-chloro-4-fluorophenyl)carbamothioyl]cyclopropanecarboxamide::SMR000669577::cid_1257250

SMILES C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c(C(N)=O)c3cc(C)cnn23)cc1

InChI Key InChIKey=NNHBHBHICWBVRN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75534   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75534BDBM75534(6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 10nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, stress response Primary Collaborators: Susan Lindquist, Whitehead Insti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75534BDBM75534(6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 55nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, stress response Primary Collaborators: Susan Lindquist, Whitehead Insti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75534BDBM75534(6-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)...)
Affinity DataIC50: 55nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent