BDBM75510 4-Amino-3-methyl-2-thioxo-2,3-dihydro-thiazole-5-carboxylic acid (2-fluoro-phenyl)-amide::4-amino-N-(2-fluorophenyl)-3-methyl-2-sulfanylidene-1,3-thiazole-5-carboxamide::4-amino-N-(2-fluorophenyl)-3-methyl-2-sulfanylidene-5-thiazolecarboxamide::4-amino-N-(2-fluorophenyl)-3-methyl-2-thioxo-4-thiazoline-5-carboxamide::4-azanyl-N-(2-fluorophenyl)-3-methyl-2-sulfanylidene-1,3-thiazole-5-carboxamide::MLS000763100::SMR000439553::cid_3769533

SMILES C=CC(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1

InChI Key InChIKey=ZAKPCTBIXWLOBB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75510   

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75510BDBM75510(6-(4-acrylamidophenyl)-7-(4-(((3-fluorooxetan-3-yl...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75510BDBM75510(6-(4-acrylamidophenyl)-7-(4-(((3-fluorooxetan-3-yl...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75510BDBM75510(6-(4-acrylamidophenyl)-7-(4-(((3-fluorooxetan-3-yl...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent