BDBM75509 1-[(5-methyl-2-thienyl)methyleneamino]-4-phenyl-4-imidazoline-2-thione::3-[(5-methyl-2-thiophenyl)methylideneamino]-5-phenyl-1H-imidazole-2-thione::3-[(5-methylthiophen-2-yl)methylideneamino]-5-phenyl-1H-imidazole-2-thione::MLS000771728::SMR000376471::cid_2109460

SMILES C=C(F)C(=O)Nc1ccc(-c2c(-c3ccc(C(=O)NCC4(F)COC4)cc3)c(C(N)=O)c3cnc(C)cn23)cc1

InChI Key InChIKey=HMLVXDCXWMVCJC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75509   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75509BDBM75509(6-(4-(2-fluoroacrylamido)phenyl)-7-(4-(((3-fluoroo...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75509BDBM75509(6-(4-(2-fluoroacrylamido)phenyl)-7-(4-(((3-fluoroo...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75509BDBM75509(6-(4-(2-fluoroacrylamido)phenyl)-7-(4-(((3-fluoroo...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent