BDBM75467 1-[4-(2-methyl-4-pyrimidinyl)phenyl]-1H-1,3-benzimidazole::1-[4-(2-methyl-4-pyrimidinyl)phenyl]benzimidazole::1-[4-(2-methylpyrimidin-4-yl)phenyl]benzimidazole::MLS000541275::SMR000126133::cid_1477797

SMILES C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(C4CN(C)C4)cn23)cc1

InChI Key InChIKey=DXNCAHDHRPSVKE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75467   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75467BDBM75467(6-(4-acrylamidophenyl)-3-(1-methylazetidin-3-yl)-7...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75467BDBM75467(6-(4-acrylamidophenyl)-3-(1-methylazetidin-3-yl)-7...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75467BDBM75467(6-(4-acrylamidophenyl)-3-(1-methylazetidin-3-yl)-7...)
Affinity DataIC50: 550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent