BDBM75462 2-(4,6-Dimethyl-pyrimidin-2-ylamino)-3-phenyl-3H-imidazol-4-ol::2-[(4,6-dimethyl-2-pyrimidinyl)amino]-3-phenyl-4-imidazolol::2-[(4,6-dimethylpyrimidin-2-yl)amino]-3-phenyl-imidazol-4-ol::2-[(4,6-dimethylpyrimidin-2-yl)amino]-3-phenylimidazol-4-ol::MLS000123954::SMR000124454::cid_920218

SMILES C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cnc(OC)cn23)cc1

InChI Key InChIKey=HGZRZNWWNWCXBT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75462   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75462BDBM75462(6-(4-acrylamidophenyl)-3-methoxy-7-(4-((6-methylpy...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75462BDBM75462(6-(4-acrylamidophenyl)-3-methoxy-7-(4-((6-methylpy...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75462BDBM75462(6-(4-acrylamidophenyl)-3-methoxy-7-(4-((6-methylpy...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent