BDBM75459 MLS000114650::N-(2-butyl-5-keto-chromeno[3,4-c]pyridin-4-yl)acetamide::N-(2-butyl-5-oxidanylidene-chromeno[3,4-c]pyridin-4-yl)ethanamide::N-(2-butyl-5-oxo-4-[1]benzopyrano[3,4-c]pyridinyl)acetamide::N-(2-butyl-5-oxochromeno[3,4-c]pyridin-4-yl)acetamide::SMR000091998::cid_4606605

SMILES C=CC(=O)N1CCc2cc(-c3c(-c4ccc(Oc5cccc(C)n5)cc4)c(C(N)=O)c4cnccn34)ccc21

InChI Key InChIKey=NRBBJNHUAQLSTQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75459   

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75459BDBM75459(6-(1-acryloylindolin-5-yl)-7-(4-((6-methylpyridin-...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75459BDBM75459(6-(1-acryloylindolin-5-yl)-7-(4-((6-methylpyridin-...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75459BDBM75459(6-(1-acryloylindolin-5-yl)-7-(4-((6-methylpyridin-...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent