BDBM75455 MLS000064056::N-(2,5-dimethoxy-4-propionamido-phenyl)benzamide::N-[2,5-dimethoxy-4-(1-oxopropylamino)phenyl]benzamide::N-[2,5-dimethoxy-4-(propanoylamino)phenyl]benzamide::N-[2,5-dimethoxy-4-(propionylamino)phenyl]benzamide::SMR000075859::cid_1291333

SMILES Cc1cn2c(-c3ccc(NC(=O)/C=C/CN(C)C)nc3)c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c2cn1

InChI Key InChIKey=OISQOKOTMCSSTC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 75455   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75455BDBM75455((E)-6-(6-(4-(dimethylamino)but-2-enamido)pyridin-3...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75455BDBM75455((E)-6-(6-(4-(dimethylamino)but-2-enamido)pyridin-3...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75455BDBM75455((E)-6-(6-(4-(dimethylamino)but-2-enamido)pyridin-3...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent