BDBM75448 3-oxidanidyl-8-phenyl-4,5-dihydro-[1,2,5]oxadiazolo[3,4-f]cinnolin-3-ium::3-oxido-8-phenyl-4,5-dihydro-[1,2,5]oxadiazolo[3,4-f]cinnolin-3-ium::3-oxido-8-phenyl-4,5-dihydrofurazano[3,4-f]cinnolin-3-ium::MLS000038932::SMR000038069::cid_2737129

SMILES C=CC(=O)Nc1ccc(-c2c(-c3ccc(Oc4cccc(C)n4)cc3)c(C(N)=O)c3cncc(C)n23)cc1

InChI Key InChIKey=GFEMPVPBJKWUBS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 75448   

TargetFibroblast growth factor receptor 2(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75448BDBM75448(tert-butyl 2-cyano-2-(6-methylpyrazin-2-yl)acetate...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75448BDBM75448(tert-butyl 2-cyano-2-(6-methylpyrazin-2-yl)acetate...)
Affinity DataIC50: 55nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75448BDBM75448(tert-butyl 2-cyano-2-(6-methylpyrazin-2-yl)acetate...)
Affinity DataIC50: 550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 75448BDBM75448(tert-butyl 2-cyano-2-(6-methylpyrazin-2-yl)acetate...)
Affinity DataIC50: 550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2026
Entry Details
US Patent