BDBM752406 US20250197405, Compound 6-P1

SMILES Cc1ncc2c(C(N)=O)c(N)n(-c3c(C)c(O)cc(F)c3C)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 752406   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 752406BDBM752406(US20250197405, Compound 6-P1)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 752406BDBM752406(US20250197405, Compound 6-P1)
Affinity DataIC50: 1.80nMAssay Description:Compound serial dilution was performed by Echo, and the final concentrations varied from 10 μM to 0.5 nM. 5 μL/well of Enzyme solution was added to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 752406BDBM752406(US20250197405, Compound 6-P1)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed