BDBM749295 US20250188094, Example 1

SMILES Cc1ccc(O)c(C)c1-n1nc(-c2nccs2)c(C(N)=O)c1N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 749295   

TargetMyelin transcription factor 1(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 749295BDBM749295(US20250188094, Example 1)
Affinity DataIC50: 10nMAssay Description:Compound serial dilution was performed by Echo, and the final concentrations vary from 10 μM to 0.5 nM. This was filled by the addition of 5 μL/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetWee1-like protein kinase(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 749295BDBM749295(US20250188094, Example 1)
Affinity DataIC50: 275nMAssay Description:Compound serial dilution is performed by Echo, and the final concentrations vary from 10 μM to 0.5 nM. This was filled by the addition of 5 μL/well o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetWee1-like protein kinase(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 749295BDBM749295(US20250188094, Example 1)
Affinity DataIC50: 500nMAssay Description:Agonist activity at FXR assessed as activation by cell based luciferase transactivation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed