BDBM747256 WO-2019/153002, TDI-005685::1-(6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2- yl)-2-hydroxyethan-1-one::US20250179079, Comparative Example A::US12522603, Compound TDI-005685

SMILES O=C(CO)N1CCc2[nH]c3c(Cl)c(Cl)ccc3c2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747256   

TargetMannosyl-oligosaccharide glucosidase(Human)
The Rockefeller University; Memorial Sloan-Kettering Cancer Center

US Patent
LigandChemical structure of BindingDB Monomer ID 747256BDBM747256(WO-2019/153002, TDI-005685 | 1-(6,7-dichloro-1,3,4...)
Affinity DataIC50: 106nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2026
Entry Details US Patent

TargetCyclic GMP-AMP synthase(Human)
Ventus Therapeutics U.S.

US Patent
LigandChemical structure of BindingDB Monomer ID 747256BDBM747256(WO-2019/153002, TDI-005685 | 1-(6,7-dichloro-1,3,4...)
Affinity DataIC50: 146nMAssay Description:Certain compounds of the present disclosure were tested for their h-cGAS inhibition activity using the methodology reported in Lama et al., “Developm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent