BDBM737273 US20250136596, Example 1

SMILES Cc1ccc(O)c(C)c1-c1cnc2[nH]c(-c3ccc(N4CCN(C)CC4)nc3C)nc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737273   

LigandChemical structure of BindingDB Monomer ID 737273BDBM737273(US20250136596, Example 1)
Affinity DataIC50: 275nMAssay Description:Compound serial dilution is performed by Echo, and the final concentrations vary from 10 μM to 0.5 nM. This was filled by the addition of 5 μL/well o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 737273BDBM737273(US20250136596, Example 1)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation in presence of 50% human serum by cell based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed