BDBM729751 US20250101040, Compound M15

SMILES Cc1nn(-c2ccc(N)nc2)c(C)c1-c1cc(N2CC3CCC(C2)O3)nc2c(-c3ccn[nH]3)cnn12

InChI Key InChIKey=QSWBJXXZKOGWNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 729751   

TargetSerine/threonine-protein kinase ATR(Human)
Jiangsu Yayo Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 729751BDBM729751(US20250101040, Compound M15)
Affinity DataIC50: 10nMAssay Description:The amount of phosphorylated P53 protein was determined using a time-resolved fluorescence system. Before the starting of the experiment, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetSerine/threonine-protein kinase ATR(Human)
Jiangsu Yayo Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 729751BDBM729751(US20250101040, Compound M15)
Affinity DataIC50: 10nMAssay Description:Inhibition of ATR (unknown origin) assessed as reduction in p53 phosphorylation level incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed