BDBM724733 US20250066388, Example 8::US20260028356, Example 8

SMILES CC%10(C)CC(c1ccc(Cl)cc1)=C9CN8CCN(c7ccc(C(=O)NS(=O)(=O)c3ccc(NC[C@@H]2C[C@](O)(CF)C2)c([N+](=O)[O-])c3)c(N6CCCOc5nc4[nH]ccc4cc56)c7)C[C@H]8COCCCOC9C%10

InChI Key InChIKey=ALJBPMWAQVXGFW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 724733   

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 724733BDBM724733(US20250066388, Example 8 | US20260028356, Example ...)
Affinity DataKi:  0.125nMAssay Description:The samples were then mixed on a shaker for 1 minute and equilibrated for an additional 3 hours at room temperature. For each assay plate, a probe/an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 724733BDBM724733(US20250066388, Example 8 | US20260028356, Example ...)
Affinity DataKi:  0.125nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 724733BDBM724733(US20250066388, Example 8 | US20260028356, Example ...)
Affinity DataKi:  0.448nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/10/2026
Entry Details US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 724733BDBM724733(US20250066388, Example 8 | US20260028356, Example ...)
Affinity DataKi:  0.448nMAssay Description:The samples were then mixed on a shaker for 1 minute and equilibrated for an additional 3 hours at room temperature. For each assay plate, a probe/an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
US Patent