BDBM72126 2-benzoyl-3-hydroxy-5-(2-methylpropyl)-4H-pyrazole-3-carboxylic acid methyl ester::2-benzoyl-3-hydroxy-5-isobutyl-2-pyrazoline-3-carboxylic acid methyl ester::MLS000570506::SMR000186933::cid_2865076::methyl 1-benzoyl-5-hydroxy-3-isobutyl-4,5-dihydro-1H-pyrazole-5-carboxylate::methyl 2-benzoyl-3-hydroxy-5-(2-methylpropyl)-4H-pyrazole-3-carboxylate::methyl 5-(2-methylpropyl)-3-oxidanyl-2-(phenylcarbonyl)-4H-pyrazole-3-carboxylate

SMILES CC(C)c1ccc(N2C[C@H](CS(C)(=O)=O)[C@H]2C)c2cnc(Nc3ccnc(-c4cnn(CC5(CC#N)CC5)c4)n3)cc12

InChI Key InChIKey=YYYIYIREDMCDOU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72126   

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 72126BDBM72126(2-(1-((4-(4-((5-isopropyl-8-((2R,3S)-2-methyl-3-((...)
Affinity DataIC50: 9.10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent