BDBM72119 1-(4-chlorobenzyl)-1-(2-furfuryl)-3-p-phenetyl-thiourea::1-[(4-chlorophenyl)methyl]-3-(4-ethoxyphenyl)-1-(2-furanylmethyl)thiourea::1-[(4-chlorophenyl)methyl]-3-(4-ethoxyphenyl)-1-(furan-2-ylmethyl)thiourea::MLS000582869::N-(4-chlorobenzyl)-N'-(4-ethoxyphenyl)-N-(2-furylmethyl)thiourea::SMR000201574::cid_2238272

SMILES CC(C)c1ccc(N2C[C@H](CS(C)(=O)=O)[C@H]2C)c2cnc(Nc3ccnc(-c4cnn(CC(F)(F)F)c4)n3)cc12

InChI Key InChIKey=GSDPWYVVVAWAJZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72119   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 72119BDBM72119(5-isopropyl-8-((2R,3S)-2-methyl-3-((methanesulfony...)
Affinity DataIC50: 1nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent