BDBM72115 (Z)-3-[2-(3,5-dimethylphenoxy)phenyl]-2-propenoic acid::(Z)-3-[2-(3,5-dimethylphenoxy)phenyl]acrylic acid::(Z)-3-[2-(3,5-dimethylphenoxy)phenyl]prop-2-enoic acid::MLS000331166::SMR000168666::cid_5399138

SMILES N#CC1(Cn2cc(-c3nccc(Nc4cc5c(C(C)C)ccc(N6C[C@H](CS(C)(=O)=O)[C@H]6C)c5cn4)n3)cn2)CC1

InChI Key InChIKey=UKEFOBQXMYMYDC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 72115   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 72115BDBM72115(1-((4-(4-((5-isopropyl-8-((2R,3S)-2-methyl-3-((met...)
Affinity DataIC50: 1nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 72115BDBM72115(1-((4-(4-((5-isopropyl-8-((2R,3S)-2-methyl-3-((met...)
Affinity DataIC50: 2.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent