BDBM714232 US20250025443, Compound 410::US20250025443, Example 266

SMILES Cc1ccc(N2CCNCC2)cc1C(=O)NC1(c2cccc3ccccc23)CC1

InChI Key InChIKey=VGRYIAFQDWWGEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 714232   

TargetReplicase polyprotein 1ab(2019-nCoV)
Comenius University Bratislava

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 714232BDBM714232(US20250025443, Compound 410 | US20250025443, Examp...)
Affinity DataIC50: 30nMAssay Description:Inhibition of SARS-CoV-2 papain-like proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetReplicase polyprotein 1a(2019-nCoV)
Clear Creek Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 714232BDBM714232(US20250025443, Compound 410 | US20250025443, Examp...)
Affinity DataIC50: 100nMAssay Description:Test compounds were assayed at 10 concentrations from 10 μM, in duplicate for the IC50 determination. The assay buffer contained 50 mM HEPES (pH 7.5)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent