BDBM704486 6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpholinoanilino)pyrazine-2-carboxamide::US20240374606, Example 39

SMILES Cn1cnc2c(-c3cnc(Nc4ccc(N5CCOCC5)cc4)c(C(N)=O)n3)cncc21

InChI Key InChIKey=WPTZSFKIESNKBN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 704486   

LigandChemical structure of BindingDB Monomer ID 704486BDBM704486(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 704486BDBM704486(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataIC50: 5nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 704486BDBM704486(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataIC50: 248nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 704486BDBM704486(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataIC50: 248nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 704486BDBM704486(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 704486BDBM704486(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetTyrosine-protein kinase Lck(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 704486BDBM704486(6-(3-Methylimidazo[4,5-c]pyridin-7-yl)-3-(4-morpho...)
Affinity DataIC50: 3.39E+4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent