BDBM695439 US12083101, Example 155

SMILES CNC(=O)c1cnc(OCCO)c(F)c1-c1c2C[C@@](Oc2cc(F)c1Cl)([C@@H]1CCCN1)c1ccccc1

InChI Key InChIKey=HUVOYQMXUNTUAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 695439   

LigandChemical structure of BindingDB Monomer ID 695439BDBM695439(US12083101, Example 155)
Affinity DataIC50: 9nMAssay Description:Avi-humanTEAD4217-434 (1 nM, produced as described in Hau et al. ChemBioChem 14, 1218, 2013) and LANCE Eu-W1024 Streptavidin (0.5 nM, PerkinElmer) we...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetTranscriptional enhancer factor TEF-1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 695439BDBM695439(US12083101, Example 155)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed