BDBM660995 6-((1H-pyrazol-4-yl)methoxy)- N-(2-chloropyimidin-5- yl)isoquinolin-1-amine::US20240101531, Example 381

SMILES Clc1ncc(Nc2nccc3cc(OCc4cn[nH]c4)ccc23)cn1

InChI Key InChIKey=UCVLAEKCHJWPDL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660995   

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660995BDBM660995(6-((1H-pyrazol-4-yl)methoxy)- N-(2-chloropyimidin-...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent