BDBM660988 2-chloro-5-((6-((1-methyl-1H- pyrazol-4- yl)methoxy)isoquinolin-1- yl)amino)pyridin-3-ol::US20240101531, Example 374

SMILES Cn1cc(COc2ccc3c(Nc4cnc(Cl)c(O)c4)nccc3c2)cn1

InChI Key InChIKey=RCXJDWZWOUXGFF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660988   

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660988BDBM660988(2-chloro-5-((6-((1-methyl-1H- pyrazol-4- yl)methox...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent