BDBM660969 N-(2-chloropyrimidin-5-yl)-6- ((3-(1,1-difluoroethyl)oxetan- 3-yl)methoxy)isoquinolin-1- amine::US20240101531, Example 355

SMILES CC(F)(F)C1(COc2ccc3c(Nc4cnc(Cl)nc4)nccc3c2)COC1

InChI Key InChIKey=IMNWBYFXFWYCMD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660969   

TargetVoltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3)(Human)
Xenon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 660969BDBM660969(N-(2-chloropyrimidin-5-yl)-6- ((3-(1,1-difluoroeth...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent