BDBM643051 N-[(3,5-Difluoropyridin-2-yl)methyl]-4-ethyl-2-[(3R)-3-methyl[1,4′-bipiperidin]-1′-yl]-1,3-thiazole-5-carboxamide::US20240000767, Example 130

SMILES CCc1nc(sc1C(=O)NCc1ncc(F)cc1F)N1CCC(CC1)N1CCC[C@@H](C)C1

InChI Key InChIKey=QONUDKILKDMADU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 643051   

TargetAlpha-2C adrenergic receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 643051BDBM643051(US20240000767, Example 130 | N-[(3,5-Difluoropyrid...)
Affinity DataIC50: 0.540nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2026
Entry Details US Patent

TargetAlpha-2C adrenergic receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 643051BDBM643051(US20240000767, Example 130 | N-[(3,5-Difluoropyrid...)
Affinity DataIC50: 0.540nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
US Patent