BDBM643032 US12540134, Example 158::US20240000767, Example 111::diamix-N-[(3,5-Difluoropyridin-2-yl)methyl]-2-[(3R)-3′-fluoro-3-methyl[1,4′-bipiperidin]-1′-yl]-1,3-thiazole-4-carboxamide
SMILES C[C@@H]1CCCN(C1)C1CCN(CC1F)c1nc(cs1)C(=O)NCc1ncc(F)cc1F
InChI Key InChIKey=XAKCPRDPHQCQFB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 643032
Affinity DataIC50: 0.490nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair