BDBM633037 US20230348456, Compound 58

SMILES Nc1c(cc(-c2cnn(c2)C2COC2)c2nc([nH]c(=O)c12)-c1ccncc1)-c1cccc2[nH]ncc12

InChI Key InChIKey=SKJWYDNAGKXQLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 633037   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 633037BDBM633037(US20230348456, Compound 58)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetMyelin transcription factor 1(Human)
Repare Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 633037BDBM633037(US20230348456, Compound 58)
Affinity DataIC50: 1nMAssay Description:Detection of Myt1 kinase activity utilized a recombinant human Myt1 kinase assay measuring the hydrolysis of ATP using a commercially available ADP-G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent