BDBM631390 US20230348421, Compound 13

SMILES CC(C)COc1ccc(CNC(=O)N(Cc2ncc(F)cn2)C2CCN(C)CC2)cc1

InChI Key InChIKey=KBFQXTVCSCMAII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 631390   

Target5-hydroxytryptamine receptor 2A(Human)
Geneora Pharma (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 631390BDBM631390(US20230348421, Compound 13 | US12527775, Compound ...)
Affinity DataIC50: 1.92nMAssay Description:CHO-K1/5-HT2A cells in the logarithmic growth phase were seeded into a 384-well plate at a density of 10000 cells per well, and cultured in a 37° C.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 631390BDBM631390(US20230348421, Compound 13 | US12527775, Compound ...)
Affinity DataKi:  55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details ArticleUS Patent

Target5-hydroxytryptamine receptor 2A(Human)
Geneora Pharma (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 631390BDBM631390(US20230348421, Compound 13 | US12527775, Compound ...)
Affinity DataKi:  55nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details ArticleUS Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Geneora Pharma (Shijiazhuang) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 631390BDBM631390(US20230348421, Compound 13 | US12527775, Compound ...)
Affinity DataIC50: 1.30E+3nMAssay Description:CHO (Chinese Hamster Ovary) cells stably expressing hERG potassium channels were taken, and hERG potassium channel currents were recorded at room tem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent