BDBM631165 US11802133, Example 14::US11802133, Example 17

SMILES FC(F)(F)c1ccc(CC2CCN(CC2)C(=O)N2CC[C@@H]3OCC(=O)N[C@H]3C2)cc1

InChI Key InChIKey=YUPLWIRVNVZRHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 631165   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 631165BDBM631165(US11802133, Example 14 | US11802133, Example 17)
Affinity DataIC50: 191nMAssay Description:The 4-NPA assay was carried out in 384 well assay plates (black with clear bottom, non-binding surface treated, Corning Ref. 3655) in a total volume ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 631165BDBM631165(US11802133, Example 14 | US11802133, Example 17)
Affinity DataIC50: 268nMAssay Description:The 4-NPA assay was carried out in 384 well assay plates (black with clear bottom, non-binding surface treated, Corning Ref. 3655) in a total volume ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 631165BDBM631165(US11802133, Example 14 | US11802133, Example 17)
Affinity DataIC50: 370nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed