BDBM631053 (S)-N-((R or S)-(5- chloro-6- cyclopropylpyridin-2- yl)(4- (trifluoromethoxy)phenyl) methyl)-2- oxoimidazolidine-4- carboxamide::US11802122, Example 40B

SMILES O=C4NC[C@@H](C(=O)N[C@@H](c1ccc(OC(F)(F)F)cc1)c3ccc(Cl)c(C2CC2)n3)N4

InChI Key InChIKey=FTFDCHIJNZAHRH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 631053   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 631053BDBM631053(US11802122, Example 40B | (S)-N-((R or S)-(5- chlo...)
Affinity DataIC50: 3.5nMAssay Description:The following buffers were used for the Qube recordings: External buffer for NaV1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent