BDBM630972 (S)—N—((R)-(3-chloro-4-fluorophenyl)(2-methylbenzo[d]thiazol-5-yl)methyl)-2-oxoimidazolidine-4-carboxamide and (S)—N—((S)-(3-chloro-4-fluorophenyl)(2-methylbenzo[d]thiazol-5-yl)methyl)-2-oxoimidazolidine-4-carboxamide::US11802122, Example 66B

SMILES Cc4nc3cc([C@H](NC(=O)[C@@H]1CNC(=O)N1)c2ccc(F)c(Cl)c2)ccc3s4

InChI Key InChIKey=WZAPWBOKQPALEV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 630972   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 630972BDBM630972(US11802122, Example 66B | (S)—N—((R)-(3-...)
Affinity DataIC50: 3.80nMAssay Description:The following buffers were used for the Qube recordings: External buffer for NaV1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
12/13/2023
Entry Details
US Patent