BDBM630944 (S)-N-((R or S)-(4- chloro-3- (trifluoromethyl)- phenyl)(4- cyanophenyl)-methyl)- 2-oxo-imidazolidine-4- carboxamide::US11802122, Example 60A::US11802122, Example 60B

SMILES N#Cc3ccc([C@H](NC(=O)[C@@H]1CNC(=O)N1)c2ccc(Cl)c(C(F)(F)F)c2)cc3

InChI Key InChIKey=BFQGCUCWHITFCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 630944   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 630944BDBM630944(US11802122, Example 60A | (S)-N-((R or S)-(4- chlo...)
Affinity DataIC50: 3.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for NaV1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent