BDBM570056 (+/−)—N-{4-[(3-chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]-3,5-difluorophenyl}-5-(methoxymethyl)-5-methyl-5,6-dihydro-4H-1,3-oxazin-2-amine::US11427578, Example 229

SMILES COCC1(C)COC(Nc2cc(F)c(Oc3ccnc4[nH]cc(Cl)c34)c(F)c2)=NC1

InChI Key InChIKey=VQCDQRMILFYGBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 570056   

LigandChemical structure of BindingDB Monomer ID 570056BDBM570056((+/−)—N-{4-[(3-chloro-1H-pyrrolo[2,3-b]...)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 570056BDBM570056((+/−)—N-{4-[(3-chloro-1H-pyrrolo[2,3-b]...)
Affinity DataIC50: 1.98E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 570056BDBM570056((+/−)—N-{4-[(3-chloro-1H-pyrrolo[2,3-b]...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent