BDBM568713 (6S)-5-[4′-Hydroxy-2-(trifluoromethyl)[1,1′-biphenyl]-4-yl]-6-methyl-3,6-dihydro-2H-1,3,4-oxadiazin-2-one::US11427553, Example 174::US11427553, Example 188
SMILES C[C@@H]1OC(=O)NN=C1c1ccc(-c2ccc(O)cc2)c(c1)C(F)(F)F
InChI Key InChIKey=QLSMQXDPLXXTTO-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 568713
Affinity DataIC50: 16nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Broad Institute of MIT and Harvard
Curated by ChEMBL
Broad Institute of MIT and Harvard
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of PI3Kdelta (unknown origin) assessed as inhibition of AKT phosphorylation by cell-based HTRF assayMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Broad Institute of MIT and Harvard
Curated by ChEMBL
Broad Institute of MIT and Harvard
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Broad Institute of MIT and Harvard
Curated by ChEMBL
Broad Institute of MIT and Harvard
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair