BDBM540247 (S)-1-(3-(1-(3-(difluoromethyl)-1-(-4-(methylol)cyclohexyl)-1H-pyrazol-4-yl)-1H-1,2,3-triazol-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl)piperidin-3-ol::US20260028337, Compound 112A

SMILES OCC1CCC(n2cc(-n3cc(-c4cnn5ccc(N6CCC[C@H](O)C6)nc45)nn3)c(C(F)F)n2)CC1

InChI Key InChIKey=HXDTYASGYWXCDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540247   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shenzhen Zhongge Biological Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 540247BDBM540247((S)-1-(3-(1-(3-(difluoromethyl)-1-(-4-(methylol)cy...)
Affinity DataIC50: 100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent