BDBM531285 US11208399, Example 44
SMILES Oc1cc(Cl)cc(Cl)c1-c1ccc(NC2CC2)nn1
InChI Key InChIKey=AESGMFAVDOKFPA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 531285
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research
Curated by ChEMBL
Novartis Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 422nMAssay Description:Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Novartis Biomedical Research
Curated by ChEMBL
Novartis Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 by cell-based ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Monocytic THP-1 cells were maintained according to providers' instructions in RPMI media as described above. Undifferentiated cells were plated a...More data for this Ligand-Target Pair