BDBM5280 5-phenyl-N-(pyridin-2-yl)-1,3-thiazol-2-amine::N-(1,3-Thiazol-2-yl)pyridin-2-amine 1::aminothiazole 3

SMILES N(c1ncc(s1)-c1ccccc1)c1ccccn1

InChI Key InChIKey=YBTSWXCHAPCPGJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5280   

TargetVascular endothelial growth factor receptor 2(Human)
Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University Mansoura

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5280BDBM5280(5-phenyl-N-(pyridin-2-yl)-1,3-thiazol-2-amine | am...)
Affinity DataIC50: 7nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University Mansoura

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5280BDBM5280(5-phenyl-N-(pyridin-2-yl)-1,3-thiazol-2-amine | am...)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2005
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University Mansoura

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5280BDBM5280(5-phenyl-N-(pyridin-2-yl)-1,3-thiazol-2-amine | am...)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2005
Entry Details Article
PubMed