BDBM523794 US11136312, Compound MS.1.22

SMILES Brc1ccc(CSc2nnc(Cc3c[nH]c4ccccc34)n2CCCc2c[nH]cn2)cc1

InChI Key InChIKey=SRWHXHFNUKAGQG-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 523794   

TargetSomatostatin receptor type 4(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523794BDBM523794(US11136312, Compound MS.1.22)
Affinity DataKi:  130nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetSomatostatin receptor type 4(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523794BDBM523794(US11136312, Compound MS.1.22)
Affinity DataKi:  130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSomatostatin receptor type 3(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523794BDBM523794(US11136312, Compound MS.1.22)
Affinity DataEC50:  166nMAssay Description:Measurement of forskolin stimulated inhibition of cAMP was performed via time-resolved fluorescence resonance energy transfer (TR-FRET) LANCE assay (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetSomatostatin receptor type 1(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523794BDBM523794(US11136312, Compound MS.1.22)
Affinity DataKi:  4.65E+3nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Southern Illinois University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 523794BDBM523794(US11136312, Compound MS.1.22)
Affinity DataKi:  7.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSomatostatin receptor type 2(Human)
Southern Illinois University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 523794BDBM523794(US11136312, Compound MS.1.22)
Affinity DataKi:  7.70E+3nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetSomatostatin receptor type 3(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523794BDBM523794(US11136312, Compound MS.1.22)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetSomatostatin receptor type 5(Human)
Board of Trustees of The Southern Illinois University

US Patent
LigandChemical structure of BindingDB Monomer ID 523794BDBM523794(US11136312, Compound MS.1.22)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive radioligand binding experiments were performed using MEMBRANE TARGET Systems (Perkin-Elmer, Boston, Mass.) for human somatostatin recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent