BDBM521010 US12534477, Compound WX042

SMILES C[C@H]1CCN1c1nc(N2CC3(C[C@@H]3C(=O)O)C2)c2c(n1)C(F)(F)CC2

InChI Key InChIKey=WPUHIWFMRNCUQZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 521010   

TargetKetohexokinase(Human)
Hangzhou Zhongmeihuadong Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 521010BDBM521010(US12534477, Compound WX042)
Affinity DataIC50: 21nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Hangzhou Zhongmeihuadong Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 521010BDBM521010(US12534477, Compound WX042)
Affinity DataIC50: 5.00E+4nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Hangzhou Zhongmeihuadong Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 521010BDBM521010(US12534477, Compound WX042)
Affinity DataIC50: 5.00E+4nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Hangzhou Zhongmeihuadong Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 521010BDBM521010(US12534477, Compound WX042)
Affinity DataIC50: 5.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Hangzhou Zhongmeihuadong Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 521010BDBM521010(US12534477, Compound WX042)
Affinity DataIC50: 5.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Hangzhou Zhongmeihuadong Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 521010BDBM521010(US12534477, Compound WX042)
Affinity DataIC50: 5.00E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent