BDBM519653 US11142525, Example 55

SMILES CCCn1cnnc1-c1cccc(n1)N1Cc2c(cc(nc2CNC)N2CCC[C@H]2C)C1=O

InChI Key InChIKey=QSVFFKYNWBAYGO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 519653   

LigandChemical structure of BindingDB Monomer ID 519653BDBM519653(US11142525, Example 55)
Affinity DataKi: <0.0600nMAssay Description:HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay (MSA). The reactions were conducted in 50 μL volumes in 96-well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 519653BDBM519653(US11142525, Example 55)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of LDH-A (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetLymphocyte cytosolic protein 2(Human)
Pfizer Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 519653BDBM519653(US11142525, Example 55)
Affinity DataIC50: 34nMAssay Description:Inhibition of human voltage-gated Na channel 1.5 by cell based patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed